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KMID : 1134820170460091053
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Journal of the Korean Society of Food Science and Nutrition
2017 Volume.46 No. 9 p.1053 ~ p.1060
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Anti-Inflammatory and Anti-Oxidative Effect of Pinus koraiensis Cone Shell Extracts
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Jin Joong-Hyun
Kwon Han-Al
Ha Ye-Jin
Heo Seok-Hyun
Lee Jeong-Min
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Abstract
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The present study examined the anti-inflammatory and anti-oxidative effects of Pinus koraiensis (PK) cone shell extracts in vitro. Anti-inflammatory and anti-oxidative effects of PK cone shell extracted with hot water, 20% ethanol (EtOH), or 50% EtOH were examined using 2,2’-azino-bis(3-ethylbenzothiazoline-6-sulphonic acid) (ABTS) radical scavenging assay, superoxide dismutase (SOD), catalase (CAT), and glutathione peroxidase (GPx) activites, as well as nitric oxide (NO) and anti-inflammatory cytokine measurements. The 20% EtOH extract of the PK cone shell decreased the NO and inflammatory cytokines secretion, and increased the ABTS radical scavenging, SOD, CAT, and GPx activities. This indicates that the 20% EtOH extract of the PK cone shell would be helpful in inflammation and oxidation systems. Therefore, the 20% EtOH extract of PK cone shell has great potential as a useful health food.
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KEYWORD
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ABTS radical scavenging, oxidant enzyme, nitric oxide, anti-inflammatory cytokines
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